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Egg fertilisation 

Egg fertilisation — the core of assisted reproduction — is the process of combining an egg (oocyte) with sperm in a highly controlled laboratory environment. The result is an embryo, which can then be transferred into the uterus to achieve pregnancy. 

At Ovumia, we apply internationally recognized best practices to ensure the highest standard of care and maximize your chances of success.

Two Main Paths: Conventional IVF and ICSI

Conventional IVF

  • In conventional IVF, sperm and eggs are placed together in a laboratory dish. Sperm naturally fertilize the eggs — a process that closely resembles natural conception, but under optimized lab conditions. 

  • This method is typically recommended when both sperm and egg quality are good — for example, in cases of unexplained infertility, mild ovulation issues, or blocked fallopian tubes (with good sperm parameters).

  • After microinjection (ICSI), the eggs are placed in an incubator, where they are cultured under carefully controlled conditions. On the day following egg collection, embryologists assess how many eggs have fertilised and continue culturing them into embryos.

Intracytoplasmic Sperm Injection (ICSI)

  • When sperm quality is reduced — e.g. low sperm count, poor motility or abnormal morphology — when sperm are surgically retrieved (for instance after vasectomy or with testicular biopsy), we use ICSI.

  • ICSI involves the direct microinjection of a single carefully selected sperm into the cytoplasm of a mature egg. This gives fertilisation the best chance, regardless of sperm concentration or mobility. 

  • After microinjection, eggs are cultured in an incubator under strictly controlled conditions. About 15–18 hours later embryologists check for fertilisation and, if successful, continue to culture the embryos. 

Who can benefit from IVF/ICSI treatment?

Egg fertilisation (IVF / ICSI) may be recommended when:

  • Natural conception is not possible – this may be due to blocked or damaged fallopian tubes, ovulation disorders, or structural abnormalities of the uterus.
  • Male factor infertility is involved – such as a low sperm count, poor sperm motility, or abnormal sperm morphology, which can prevent natural fertilisation.
  • Previous fertility treatments have not been successful, or sperm needs to be retrieved surgically.

What to know before starting

  • Each couple is unique — fertilisation method (IVF or ICSI) is chosen based on individual assessment.
  • Even with the best lab conditions, not every egg becomes a viable embryo.
  • Thanks to modern laboratory techniques (IVF and ICSI) and individualised treatment planning, the majority of couples are able to achieve pregnancy even when facing significant fertility challenges.

Embryo Culture

Let us guide you on your path to parenthood.